Patch, gel, tablet or cream
Estradiol
From $70/mo
Hot flashes, night sweats & vaginal dryness
Actual prescription vial and label appearance will vary.
Some forms are compounded. Compounded medications are not FDA-approved.
Actual prescription vial and label appearance will vary.
Biest 50:50 · Menopause
Two estrogens, blended for you.
Biest 50:50 is a compounded blend of equal parts estradiol and estriol, customized by your provider. It’s prescribed only if a licensed provider decides it’s right for you. Compounded medications are not FDA-approved. Results vary.
Get startedPricing shown in your free online visit
Some forms are compounded. Compounded medications are not FDA-approved. A licensed provider decides if treatment is right for you.
Actual prescription vial and label appearance will vary.
OnlyHuman Rx / Menopause
Compounded blend · Provider-guided care
Biest 50:50
Pricing shown in your free online visit
Biest 50:50 is a compounded blend of estradiol and estriol, customized by your provider. Compounded medications are not FDA-approved.
Some forms are compounded. Compounded medications are not FDA-approved.
No insurance requiredNo membership or hidden feesUnlimited support
Save 10% with a 3-month plan
Plans from $70, $95 or $125 a month, depending on what your provider prescribes. Compare plansStart Today
Free online visit · You’re not charged unless a provider prescribes
What is Biest 50:50?
Biest 50:50 is a compounded estrogen made from equal parts of two estrogens:
- Estradiol: the main and strongest estrogen the body makes during the reproductive years.
- Estriol: a much weaker estrogen, made mostly during pregnancy.
Subject to medical approval. A prescription is required. Final eligibility is determined online by a licensed healthcare provider.
Pay over time with Klarna · Affirm · Afterpay
FSA/HSA eligibility and coverage varies by plan provider.
Benefits
A customized estrogen blend, with a licensed provider checking in along the way.
Get started
Two Estrogens, One Blend
Equal parts estradiol, the body's strongest estrogen, and estriol, a much weaker one.
Customized by Your Provider
Your provider sets the dose for you based on your symptoms and health history.
Ongoing Check-Ins
Your provider checks in and adjusts your plan as needed. Results vary.
Paired With Progesterone When Needed
If you still have a uterus, your provider will usually prescribe progesterone alongside any estrogen.
Results vary. Treatment works best alongside balanced meals, movement, and sleep.
How it works
- 01
Online Intake
Choose a program and answer a short online health questionnaire. It’s free and only takes a few minutes.
- 02
Provider Review
A licensed provider reviews your answers and health history to decide whether treatment is right for you.
- 03
Delivered to Your Door
If prescribed, your medication is prepared by a licensed pharmacy and shipped to you in discreet packaging.
The Health Guide
OnlyHuman Health Guide
Real answers for your health journey.
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Actual prescription vial and label appearance will vary.
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Your questions, answered
Frequently asked questions.
What is Biest 50:50?
Biest 50:50 is a compounded estrogen made from equal parts of two estrogens:
- Estradiol: the main and strongest estrogen the body makes during the reproductive years.
- Estriol: a much weaker estrogen, made mostly during pregnancy.
Is Biest FDA-approved?
No. Biest 50:50 is a compounded blend of estradiol and estriol, customized by your provider. Compounded medications are not FDA-approved.
Do I need progesterone with Biest?
For women who still have a uterus, estrogen alone can thicken the uterine lining and raise the risk of endometrial cancer. Progesterone prevents that, so it's usually prescribed alongside estrogen. Your provider will decide what's right for you.
Can I take Biest with my other medications?
List all medications and supplements in your intake. A licensed provider will review them before prescribing.